Objective: To determine if blood neurofilament light chain (NfL) protein can discriminate between Parkinson disease (PD) and atypical parkinsonian disorders (APD) with equally high diagnostic accuracy as CSF NfL, and can therefore improve the diagnostic workup of parkinsonian disorders. Methods: The study included 3 independent prospective...

Parkinson’s Disease or PD is a neurodegenerative disorder; it may progress slowly but worsens over time.  Symptoms in the advanced stages of this disease can include slowed movements, tremors, and memory loss.  Many sufferers find themselves increasingly dependent on their caregivers as their condition declines. ...