Study Finds Genetic Risk of Stroke Associated with Cognitive Ability


Objectives: We investigated the correlation between polygenic risk of ischemic stroke (and its subtypes) and cognitive ability in 3 relatively healthy Scottish cohorts: the Lothian Birth Cohort 1936 (LBC1936), the Lothian Birth Cohort 1921 (LBC1921), and Generation Scotland: Scottish Family Health Study (GS).

Methods: Polygenic risk scores for ischemic stroke were created in LBC1936 (n = 1005),