Description Palm Beach Neurological Center is participating in a global clinical research study to prevent or delay Alzheimer’s disease in cognitively healthy, older individuals that have been identified with one or two major genetic risk factors for the onset of Alzheimer’s disease. The Generation Study 2 is...
Description A global clinical research study assessing the effectiveness and safety of an investigational medication designed to slow the progression of early Alzheimer’s disease. The ENGAGE study is split into two phases: a placebo-controlled phase, and an optional long-term extension phase. In the placebo-controlled phase, eligible participants will...
Description The MissionAD study program is a clinical research program testing an investigational drug for the early stages of Alzheimer’s disease. (“Investigational” means the drug isn’t yet approved for use by the public.) Doctors are studying this investigational drug to make sure it is safe and...
Description The "IDEAS" Study stands for Imaging Dementia-Evidence for Amyloid Scanning. The purpose of this study is to improve the way doctors are able to take images of the brain and better treat dementia and memory-related conditions. Over 8,000 medicare patients are expected to be in the study,...
Description Many people who have Alzheimer’s also have irregular patterns of sleeping at night and napping during the day. A clinical research study is studying an investigational medication in people with Alzheimer’s disease and sleep problems. Qualified study volunteers may receive: Study medication Study-related medical care Transportation...
Dementia with Lewy Bodies (DLB) affects over 1 million people in the United States. It is caused by the buildup of abnormal protein clusters, known as “Lewy Bodies,” within the brain and is characterized by fluctuations in cognitive ability, particularly alertness and attention. Many dementia...
Most individuals with Parkinson’s disease use levodopa as treatment. It is usually taken in pill form, however long-term usage can lessen the effectiveness of the drug leading to off episodes. In these off episodes, individuals with Parkinson’s suffer from slowness, stiffness and tremors. CVT-301, the medication...
What is Mild Cognitive Impairment (MCI)? Mild Cognitive Impairment is a condition in which a person has memory loss or thinking problems that are worse than those caused by normal aging, but not bad enough to interfere with daily activities. A person with MCI has a...
Randomized, double-blind, placebo-controlled, fixed dose study of Lu AE58054 in patients with mild to moderate Alzheimer's disease treated with Donepezil. This is a 28 week study in which qualified participants will take the investigational medication or placebo ( a dummy capsule without an active ingredient )...
ABSTRACT Objectives: We investigated the correlation between polygenic risk of ischemic stroke (and its subtypes) and cognitive ability in 3 relatively healthy Scottish cohorts: the Lothian Birth Cohort 1936 (LBC1936), the Lothian Birth Cohort 1921 (LBC1921), and Generation Scotland: Scottish Family Health Study (GS). Methods: Polygenic risk...