Body composition status and the risk of migraine

ABSTRACT

Objective: To evaluate the association between migraine and body composition status as estimated based on body mass index and WHO physical status categories.

 

Methods: Systematic electronic database searches were conducted for relevant studies. Two independent reviewers performed data extraction and quality appraisal. Odds ratios (OR) and confidence intervals (CI) were pooled using a random effects model.

Neuropsychiatric symptoms predict hypometabolism in preclinical Alzheimer disease

ABSTRACT

Objective: To identify regional brain metabolic dysfunctions associated with neuropsychiatric symptoms (NPS) in preclinical Alzheimer disease (AD).

 

Methods: We stratified 115 cognitively normal individuals into preclinical AD (both amyloid and tau pathologies present), asymptomatic at risk for AD (either amyloid or tau pathology present),

Parental family history of dementia in relation to subclinical brain disease and dementia risk

Objective: To determine the association of parental family history with risk of dementia by age at onset and sex of affected parent in a population-based cohort.

 

Methods: From 2000 to 2002, we assessed parental history of dementia in participants without dementia of the Rotterdam Study. We investigated associations of parental history with risk of dementia until 2015,