Behavioral-variant frontotemporal dementia

ABSTRACT

Objective: To identify distinct behavioral phenotypes of behavioral-variant frontotemporal dementia (bvFTD) and to elucidate differences in functional, neuroimaging, and progression to residential care placement.

Methods: Eighty-eight patients with bvFTD were included in a cluster analysis applying levels of disinhibition and apathy (Cambridge Behavioural Inventory-Revised) to identify phenotypic subgroups. Between-group (Kruskal-Wallis,

Slowing Gait and Risk for Cognitive Impairment

Originally posted on www.neurology.org

Methods: We assessed a cohort of older adults (n = 175, mean age 73 years, 57% female, 65% white) with repeated measures of gait speed over 14 years, MRI for gray matter volume (GMV) at year 10 or 11, and adjudicated cognitive status at year 14. Gait slowing was calculated by bayesian slopes corrected for intercepts,

New Evidence that the Prevalence of Dementia is Declining

A new analysis of data from a database on persons aged 65 or older found that the prevalence of dementia went from 11.6 percent in 2000 to 8.8 percent in 2012, a decline attributed in part to an increase in educational attainment among the later-born group.

Researchers have long been warning about a coming tsunami of dementia as the population of older people grows,

Dementia risk in renal dysfunction

ABSTRACT

Objective: Renal dysfunction has been linked with increased risk for cognitive impairment and dementia, but studies are conflicting. For that reason, the aim of the present systematic review and meta-analysis is to summarize the best available evidence on the prospective association between potential markers of renal dysfunction and development of cognitive impairment or dementia.