Dementia with Lewy Bodies (DLB) affects over 1 million people in the United States. It is caused by the buildup of abnormal protein clusters, known as “Lewy Bodies,” within the brain and is characterized by fluctuations in cognitive ability, particularly alertness and attention. Many dementia with Lewy Bodies patients also have visual hallucinations and REM sleep behavior disorder.
Mild Cognitive Impairment is a condition in which a person has memory loss or thinking problems that are worse than those caused by normal aging, but not bad enough to interfere with daily activities. A person with MCI has a higher risk of developing Alzheimer’s disease,
This is a 28 week study in which qualified participants will take the investigational medication or placebo ( a dummy capsule without an active ingredient ) once daily by mouth.
Potential patients must have been receiving a drug containing Donepezil for the last 6 months,
Background: We sought to determine the usefulness of sonography in the detection of nerve involvement in patients with vasculitic neuropathy.
Methods: We enrolled 16 consecutive patients with vasculitic neuropathy (11 systemic vasculitis and 5 single organ peripheral nerve vasculitis), who met the diagnostic criteria of the Peripheral Nerve Society,
Background: Delay in recognition and treatment of inflammatory neuropathies increases morbidity and mortality. We have developed and standardized 3 clinical screening criteria that rapidly detect inflammatory neuropathies.
Methods: We reviewed all patients with definite large fiber neuropathy in 2 different patient populations: 1 from a private neurology clinic and the other from a tertiary care center.
A study to evaluate an investigational drug designed to inhibit receptors that are believed to contribute to migraine attacks.
This study lasts up to 55 weeks, in which participants will be screened, go through two phases of treatment and have a follow-up visit.
Study Treatment Phase – Part One – 12 Weeks
Participants will be randomly assigned to receive the investigational drug or a placebo.